Tampa Tribune
November 1996
Shock therapy debate revived
She's 68, but she looks younger. Her eyes sparkle with childlike
curiosity and her voice is a honeyed, sassy whisper. Southern
through and through, that's Madeline LaDrue - although that's not
her real name. She wants to remain anonymous, even though a few of
her friends know.
They know that Madeline's depression is being treated with
electroconvulsive therapy at St. Joseph's Hospital in Tampa. Once
every six weeks, since March. And that it "gave me my life
back,'' Madeline says cheerily. "If people think it's barbaric
today, well, they're ignorant.''
Electroconvulsive therapy - which practitioners prefer to the term
shock therapy - means many things to many people. Proponents say
that it is enormously effective in the short run and that it may
be far safer than antidepressant drugs. Opponents argue it damages
the brain and that the temporary relief of depression is no
substitute for some patients' profound and permanent memory loss.
Either way, electroconvulsive therapy has returned to mainstream
medicine. In the Tampa Bay area, a handful of hospital-based
psychiatrists perform the procedure on their most severely
depressed patients, many of them older, most suicidal and
psychotic. All are clearly unresponsive to medication. The typical
course is a series of six to 12 treatments over a period of a few
weeks. Then the therapy is reduced to one treatment a month or
less, depending on the patient's relapse rate.
Memory loss and
confusion are common side effects of shock therapy, and doctors
admit there is no way to predict the severity of a patient's loss.
It ranges from slight, forgetting only those events just before
and after treatment, to severe, forgetting incidents and
information acquired months or years before.
Nonetheless, "it's the best thing that ever happened to me,''
says Madeline, as she lies on a bed minutes before her treatment.
James Adams, medical director of psychiatric services at St.
Joseph's Hospital, and Malcolm Klein, an anesthesiologist, are at
her side. So are several nurses.
They will monitor her blood pressure, her respiratory rate, her
heart rate and blood oxygen level throughout the procedure. They
will also administer a muscle relaxer and a very short-acting
anesthetic; for three to five minutes, a machine will do the
breathing for her.
But it is the electrodes on Madeline's temples that are at the
center of all this attention. With a nod from James, a box the
size of a stereo receiver delivers a pulsing, electrical charge
about one-fourth the power of that used to revive a heart by
electrical stimulus. The charge surges through her brain, inducing
a seizure or convulsion. For 57 seconds. That goes virtually
undetected by observers except for the slight strain of a muscle
in her neck - and a paper strip from the electroconvulsive therapy
machine. It spits out a jagged squiggle, similar to seismograph
recordings of an earthquake.
Within five minutes, Madeline is awake and answering questions.
And smiling at the people around her.
"I think of it as ECT of the heart and ... nobody thinks anything
about starting the heart with an electrical shock after heart
surgery,'' says Klein, who has worked with shock therapy patients
since 1992.
Adams, who has administered the therapy since 1990, is likewise
pragmatic. He considers it a treatment of last resort, only for
the severely ill, despite the remarkable success he has seen in
his psychiatric practice. Up to 95 percent of his patients felt
their depression subside after the therapy.
Yet science continues to wrestle with precisely why it works, and
how. And the public continues to perceive the procedure as a
harrowing, horrible form of torture, like that depicted in the
movie, "One Flew Over the Cuckoo's Nest.''
Electroconvulsive therapy was introduced in 1938 by an Italian
scientist who tried it on several patients. It apparently relieved
their depression and quickly became something of a psychiatric
fad, applied to the mentally ill with little regard for accurate
diagnosis or side effects.
By the late 1960s, the therapy had fallen out of favor. Only in
the last 10 to 15 years has it become more acceptable, as
researchers have modified the electrical charge and minimized the
patient's discomfort. Nowadays, for example, patients get a muscle
relaxer. For years they didn't, and fractured bones often followed
the induced seizure.
The technique may be modified in some patients, since an
electrical charge can dramatically alter blood pressure or heart
beat. Nevertheless, many practitioners feel it is less risky than
drugs, particularly in patients whose conditions are complicated
by antidepressants: pregnant women, the elderly, the seriously
physically ill.
Harold Sackeim, chief of the department of biological psychiatry
at New York State Psychiatric Institute and one of the country's
leading electroconvulsive therapy researchers, theorizes that the
brain of a depressed person is actually working too hard and too
long, like an engine that idles too fast. The therapy slows the
idle. As strange as it sounds, Sackeim says, research on
individuals who are catatonic - who don't respond to their
environment - show that their brains are "literally buzzing
away.''
"I have patients who have appeared on Broadway the night of their
ECT,'' Sackeim says.
In England and Sweden, electroconvulsive therapy is a first-line
treatment. If you are hospitalized for depression, shock therapy
is among your first choices, not your last, Sackeim says. In the
United States, the therapy is far less common. About 50,000
patients a year receive the therapy and, without insurance
coverage, it costs about $500 a treatment.
It also requires the patient's signature on a lengthy legal
document. "To my understanding, it is the most detailed consent
form in medicine,'' Sackeim says.
In fact, American Psychiatric Association guidelines for
electroconvulsive therapy, issued in 1990, fill more than 200
pages. And at St. Joseph's Hospital, no patient can receive it
unless they first view a videotape of the procedure and sign a
complex consent form. Furthermore, Adams says, a patient who is
ruled incompetent cannot receive the therapy unless a motion
requesting the procedure is filed in court.
This does not impress Linda Andre, a single mother from New York
City who heads the Committee for Truth in Psychiatry. This group
of about 500 members, many former recipients of the treatment,
asserts that patients who receive shock therapy are poorly
informed about the consequences; specifically, they aren't told
about the risk for profound memory loss.
The group lobbies legislators, demanding more detailed informed
consent laws and railing at political and medical bureaucracies
which, Andre says, tend to regard members of the organization as
"just plain crazy.''
"Shock therapy is ... Russian roulette,'' says Andre, who in the
early 1980s was treated with electroconvulsive therapy during an
involuntary hospitalization she can't recall. The result: Andre
says she lost memory, intelligence, personality.
"I don't feel like the me I was supposed to be,'' she says sadly.
Andre also says her problems have been medically documented, yet
the scientific community is clearly unmoved by her complaints. One
prominent researcher, Andre says, poked her at a convention and
pronounced, "You're alive, aren't you?''
Another outspoken opponent of electroconvulsive therapy, author
and psychiatrist Peter Breggin, is even more direct. He says it
should be outlawed. Despite attempts at such regulation, the
therapy is not illegal anywhere in the United States, and Texas is
the only state where it is restricted by law. It cannot be
performed on patients 16 or younger.
"My colleagues have done as much brain damage to patients as the
public and the legal profession will allow them to do,'' says
Breggin, a professor in the counseling department at Johns Hopkins
University in Baltimore.
"Of course, if you take the average person and make them
retarded, they are going to be grinning. It's because their brains
are grossly damaged during this procedure. And sure ... it
produces an unrealistic euphoria.
"You can't find 20 patients who've been helped by ECT. That's a
farce.''
Sackeim is quick to react to Breggin's comments. He says that the
term "brain damage'' applied to the therapy is inaccurate at best
and silly at worst, and "completely out of keeping with the
scientific understanding of ECT.''
And though he agrees that memory loss is among the side effects
associated with shock therapy, Sackeim says that there is often
improvement in attention and concentration.
Furthermore, "here at Columbia, we are some of our most severe
critics,'' Sackeim says. He is in the midst of a $4 million study
funded by the National Institute of Mental Health. His goal is to
determine how and why depressed patients experience a relapse, and
whether electroconvulsive therapy makes a difference.
Madeline is merely glad that today, and for the next few weeks, it
seems to work for her. She hasn't lost any memory. In fact, she
thinks her memory is better than before. And after a lifetime
spent addicted to diet pills - including 13 years experimenting
"with every antidepressant in the world'' - Madeline is convinced
that shock therapy is her salvation.
She no longer needs that garbage bag full of pills she once kept
in the trunk of her car.
"By the time I got here, even if someone said you were going to
lose memory, I didn't care,'' she says. "I had nothing to lose.
"All I know is I don't dread waking up anymore. I'm not
depressed. I've lost 22 pounds. I would just like people to know
that if they are at the end of their rope, they should give it a
try. No, it's not a cure, but it's a good treatment.''
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